Monday, 27 October, 2025
A recent study of Bangladeshi scientists has unveiled a breakthrough nanomaterial capable of delivering cardiovascular medicine such as felodipine more efficiently, offering new hope for heart patients.
Published in the Nanoscale journal of the Royal Society of Chemistry, the research introduces a gallium nitride-based nanomaterial, known as GaNF, which can safely carry and release felodipine within the human body.
Felodipine is a widely used drug for treating high blood pressure and other cardiovascular diseases.
The research team comprised Prof. Md Kabir Uddin Sikder from the Department of Physics, Jahangirnagar University; Aoly Ur Rahman from the Department of Nanomaterials and Ceramic Engineering, Bangladesh University of Engineering and Technology (BUET); Md Kazi Rokunuzzaman from The Ohio State University, USA; D.M. Saaduzzaman from Rensselaer Polytechnic Institute, USA; Mohammad Sadiqur Rahman from Dhaka University of Engineering and Technology (DUET); Muzzakkir Amin from the University of California, USA; and Syed Mahedi Hasan from the Florida Institute of Technology, USA.
Using advanced computer simulations, the researchers compared three nanomaterials — boron nitride, aluminium nitride, and gallium nitride — to determine which could transport felodipine most effectively.
The findings showed that gallium nitride fullerene (GaNF) formed the strongest and most stable bond with the drug, enabling controlled release and improved therapeutic efficiency.
The study further revealed that GaNF responds effectively to near-infrared light, which can penetrate human tissue, allowing real-time tracking of the drug’s movement within the body.
“Our study demonstrates that GaNF can serve as a powerful and stable nanocarrier for cardiovascular drugs like felodipine,” said corresponding author Aoly Ur Rahman.
He noted that the material’s biocompatibility and non-toxic nature make it suitable for safe and controlled drug delivery, minimising side effects while enabling both superficial and deep-tissue therapies.
Rahman expressed optimism that the findings could pave the way for safer and more targeted drug delivery systems in the future.
The research was supported by the Biophysics Laboratory of Jahangirnagar University under the supervision of Prof. Dr Md Kabir Uddin Sikder.
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A recent study of Bangladeshi scientists has unveiled a breakthrough nanomaterial capable of delivering cardiovascular medicine such as felodipine more efficiently, offering new hope for heart patients.
Published in the Nanoscale journal of the Royal Society of Chemistry, the research introduces a gallium nitride-based nanomaterial, known as GaNF, which can safely carry and release felodipine within the human body.
Felodipine is a widely used drug for treating high blood pressure and other cardiovascular diseases.
The research team comprised Prof. Md Kabir Uddin Sikder from the Department of Physics, Jahangirnagar University; Aoly Ur Rahman from the Department of Nanomaterials and Ceramic Engineering, Bangladesh University of Engineering and Technology (BUET); Md Kazi Rokunuzzaman from The Ohio State University, USA; D.M. Saaduzzaman from Rensselaer Polytechnic Institute, USA; Mohammad Sadiqur Rahman from Dhaka University of Engineering and Technology (DUET); Muzzakkir Amin from the University of California, USA; and Syed Mahedi Hasan from the Florida Institute of Technology, USA.
Using advanced computer simulations, the researchers compared three nanomaterials — boron nitride, aluminium nitride, and gallium nitride — to determine which could transport felodipine most effectively.
The findings showed that gallium nitride fullerene (GaNF) formed the strongest and most stable bond with the drug, enabling controlled release and improved therapeutic efficiency.
The study further revealed that GaNF responds effectively to near-infrared light, which can penetrate human tissue, allowing real-time tracking of the drug’s movement within the body.
“Our study demonstrates that GaNF can serve as a powerful and stable nanocarrier for cardiovascular drugs like felodipine,” said corresponding author Aoly Ur Rahman.
He noted that the material’s biocompatibility and non-toxic nature make it suitable for safe and controlled drug delivery, minimising side effects while enabling both superficial and deep-tissue therapies.
Rahman expressed optimism that the findings could pave the way for safer and more targeted drug delivery systems in the future.
The research was supported by the Biophysics Laboratory of Jahangirnagar University under the supervision of Prof. Dr Md Kabir Uddin Sikder.
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